Peptide Structures

Primary Structure

  • Protein have multiple levels of structure.

  • The most basic is its primary structure.

  • A protein's primary structure is simply the order of its amino acids.

  • Note that this order is always written from amino end to carboxyl end (by convention).

Secondary Structure

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  • Protein secondary structure refers to certain common repeating structures found in proteins. There are two types of secondary structures: alpha-helix and beta-pleated sheet.

  • An alpha-helix is a tight helix formed out of the polypeptide chain. The polypeptide main chain makes up the central structure, and the side chains extend out and away from the helix.

  • The helix makes a complete turn every 3.6 amino acids.

  • The helix is right-handed; it twists in a clockwise direction

  • B-pleated sheets are the other type of secondary structure. They can be either parallel or anti-parallel.

Tertiary Structure

  • Tertiary structure is the full 3-dimensional folded structure of the polypeptide chain.








Quaternary Structure

  • Quartenary structure is only present if there is more than one polypeptide chain.

  • With multiple polypeptide chains, quartenary structure is their interconnections and organization.












Amino Acids

  • AMINO ACIDS are the "building Blocks" of the body.

  • Besides building cells and repairing tissue, they form antibodies to combat invading bacteria & viruses; they are part of the enzyme & hormonal system; they build nucleoproteins (RNA & DNA); they carry oxygen throughout the body and participate in muscle activity.

  • When protein is broken down by digestion the result is 22 known amino acids.

  • Eight are essential (cannot be manufactured by the body) the rest are non-essential ( can be manufactured by the body with proper nutrition).

Click to view amino acids